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High Throughput Screening Targeting the Dengue NS3-NS5 Interface Identifies Antivirals against Dengue, Zika and West Nile Viruses

Dengue virus (DENV) threatens almost 70% of the world’s population, with no effective therapeutic currently available and controversy surrounding the one approved vaccine. A key factor in dengue viral replication is the interaction between DENV nonstructural proteins (NS) 5 and 3 (NS3) in the infect...

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Detalles Bibliográficos
Autores principales:	Yang, Sundy N. Y., Maher, Belinda, Wang, Chunxiao, Wagstaff, Kylie M., Fraser, Johanna E., Jans, David A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870125/ https://www.ncbi.nlm.nih.gov/pubmed/35203378 http://dx.doi.org/10.3390/cells11040730

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