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The Bright and the Dark Side of TGF-β Signaling in Hepatocellular Carcinoma: Mechanisms, Dysregulation, and Therapeutic Implications

SIMPLE SUMMARY: Transforming growth factor β (TGF-β) signaling is a preeminent regulator of diverse cellular and physiological processes. Frequent dysregulation of TGF-β signaling has been implicated in cancer. In hepatocellular carcinoma (HCC), the most prevalent form of primary liver cancer, the a...

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Detalles Bibliográficos
Autores principales: Gungor, Medine Zeynep, Uysal, Merve, Senturk, Serif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870127/
https://www.ncbi.nlm.nih.gov/pubmed/35205692
http://dx.doi.org/10.3390/cancers14040940