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Inducing Biomechanical Heterogeneity in Brain Tumor Modeling by MR Elastography: Effects on Tumor Growth, Vascular Density and Delivery of Therapeutics

SIMPLE SUMMARY: Biomechanical forces aggravate brain tumor progression. In this study, magnetic resonance elastography (MRE) is employed to extract tissue biomechanical properties from five glioblastoma patients and a healthy subject, and data are incorporated in a mathematical model that simulates...

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Detalles Bibliográficos
Autores principales: Harkos, Constantinos, Svensson, Siri Fløgstad, Emblem, Kyrre E., Stylianopoulos, Triantafyllos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870149/
https://www.ncbi.nlm.nih.gov/pubmed/35205632
http://dx.doi.org/10.3390/cancers14040884