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The Role of SMAD4 Inactivation in Epithelial–Mesenchymal Plasticity of Pancreatic Ductal Adenocarcinoma: The Missing Link?

SIMPLE SUMMARY: Pancreatic ductal adenocarcinoma (PDAC) is currently one of the deadliest cancers. Despite the progress that has been made in the research of patient care and the understanding of pancreatic cancer, the survival rate remains mediocre. SMAD4, a tumor-suppressor gene, is specifically i...

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Detalles Bibliográficos
Autores principales: Racu, Marie-Lucie, Lebrun, Laetitia, Schiavo, Andrea Alex, Van Campenhout, Claude, De Clercq, Sarah, Absil, Lara, Minguijon Perez, Esmeralda, Maris, Calliope, Decaestecker, Christine, Salmon, Isabelle, D’Haene, Nicky
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870198/
https://www.ncbi.nlm.nih.gov/pubmed/35205719
http://dx.doi.org/10.3390/cancers14040973