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Discordant Genome Assemblies Drastically Alter the Interpretation of Single-Cell RNA Sequencing Data Which Can Be Mitigated by a Novel Integration Method

Advances in sequencing and assembly technology have led to the creation of genome assemblies for a wide variety of non-model organisms. The rapid production and proliferation of updated, novel assembly versions can create vexing problems for researchers when multiple-genome assembly versions are ava...

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Detalles Bibliográficos
Autores principales: Potts, Helen G., Lemieux, Madeleine E., Rice, Edward S., Warren, Wesley, Choudhury, Robin P., Mommersteeg, Mathilda T. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870202/
https://www.ncbi.nlm.nih.gov/pubmed/35203259
http://dx.doi.org/10.3390/cells11040608