CRISPR/Cas9 Mediated Knockout of Cyclooxygenase-2 Gene Inhibits Invasiveness in A2058 Melanoma Cells

The inducible isoenzyme cyclooxygenase-2 (COX-2) is an important hub in cellular signaling, which contributes to tumor progression by modulating and enhancing a pro-inflammatory tumor microenvironment, tumor growth, apoptosis resistance, angiogenesis and metastasis. In order to understand the role o...

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Detalles Bibliográficos
Autores principales: Haase-Kohn, Cathleen, Laube, Markus, Donat, Cornelius K., Belter, Birgit, Pietzsch, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870212/
https://www.ncbi.nlm.nih.gov/pubmed/35203404
http://dx.doi.org/10.3390/cells11040749

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870212/
https://www.ncbi.nlm.nih.gov/pubmed/35203404
http://dx.doi.org/10.3390/cells11040749

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