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CRISPR/Cas9 Mediated Knockout of Cyclooxygenase-2 Gene Inhibits Invasiveness in A2058 Melanoma Cells

The inducible isoenzyme cyclooxygenase-2 (COX-2) is an important hub in cellular signaling, which contributes to tumor progression by modulating and enhancing a pro-inflammatory tumor microenvironment, tumor growth, apoptosis resistance, angiogenesis and metastasis. In order to understand the role o...

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Detalles Bibliográficos
Autores principales:	Haase-Kohn, Cathleen, Laube, Markus, Donat, Cornelius K., Belter, Birgit, Pietzsch, Jens
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870212/ https://www.ncbi.nlm.nih.gov/pubmed/35203404 http://dx.doi.org/10.3390/cells11040749

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