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Bone Marrow Stroma-Induced Transcriptome and Regulome Signatures of Multiple Myeloma

SIMPLE SUMMARY: The bone marrow (BM) microenvironment provides a protective sanctuary for multiple myeloma (MM) against therapeutic agents. MM cells interact with BM stromal cells (BMSCs) and the interaction is sufficient to confer de novo multi-drug resistance with epigenetic mechanisms as one of t...

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Detalles Bibliográficos
Autores principales: Dziadowicz, Sebastian A., Wang, Lei, Akhter, Halima, Aesoph, Drake, Sharma, Tulika, Adjeroh, Donald A., Hazlehurst, Lori A., Hu, Gangqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870223/
https://www.ncbi.nlm.nih.gov/pubmed/35205675
http://dx.doi.org/10.3390/cancers14040927