Cargando…

Bone Marrow Stroma-Induced Transcriptome and Regulome Signatures of Multiple Myeloma

SIMPLE SUMMARY: The bone marrow (BM) microenvironment provides a protective sanctuary for multiple myeloma (MM) against therapeutic agents. MM cells interact with BM stromal cells (BMSCs) and the interaction is sufficient to confer de novo multi-drug resistance with epigenetic mechanisms as one of t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dziadowicz, Sebastian A., Wang, Lei, Akhter, Halima, Aesoph, Drake, Sharma, Tulika, Adjeroh, Donald A., Hazlehurst, Lori A., Hu, Gangqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870223/ https://www.ncbi.nlm.nih.gov/pubmed/35205675 http://dx.doi.org/10.3390/cancers14040927

Ejemplares similares

Inflammatory Bone Marrow Mesenchymal Stem Cells in Multiple Myeloma: Transcriptional Signature and In Vitro Modeling
por: Wang, Lei, et al.
Publicado: (2023)

Interleukin-27-dependent transcriptome signatures during neonatal sepsis
por: Povroznik, Jessica M., et al.
Publicado: (2023)

Emergence of Resistance to MTI-101 Selects for a MET Genotype and Phenotype in EGFR Driven PC-9 and PTEN Deleted H446 Lung Cancer Cell Lines
por: Jones, Clark, et al.
Publicado: (2022)

Genomic characterization of the adolescent idiopathic scoliosis-associated transcriptome and regulome
por: Makki, Nadja, et al.
Publicado: (2020)

miRegulome: a knowledge-base of miRNA regulomics and analysis
por: Barh, Debmalya, et al.
Publicado: (2015)

Integrative analyses of single-cell transcriptome and regulome using MAESTRO
por: Wang, Chenfei, et al.
Publicado: (2020)

The differential disease regulome
por: Sandve, Geir K, et al.
Publicado: (2011)

Transient Receptor Potential C 1/4/5 Is a Determinant of MTI-101 Induced Calcium Influx and Cell Death in Multiple Myeloma
por: Elzamzamy, Osama M., et al.
Publicado: (2021)

The Pancreatic Islet Regulome Browser
por: Mularoni, Loris, et al.
Publicado: (2017)

A reference single-cell regulomic and transcriptomic map of cynomolgus monkeys
por: Qu, Jiao, et al.
Publicado: (2022)

Combined Noncoding RNA-mRNA Regulomics Signature in Reprogramming and Pluripotency in iPSCs
por: Salloum-Asfar, Salam, et al.
Publicado: (2022)

The Nutrient Response Transcriptional Regulome of Arabidopsis
por: Brumbarova, Tzvetina, et al.
Publicado: (2019)

On the NF-Y regulome as in ENCODE (2019)
por: Ronzio, Mirko, et al.
Publicado: (2020)

The temporal dynamics of the sea urchin regulome
por: Feuda, Roberto
Publicado: (2022)

Stroma Transcriptomic and Proteomic Profile of Prostate Cancer Metastasis Xenograft Models Reveals Prognostic Value of Stroma Signatures
por: Karkampouna, Sofia, et al.
Publicado: (2020)

Genetic variability of microRNA regulome in human
por: Obsteter, Jana, et al.
Publicado: (2015)

Functional Metabolomics Describes the Yeast Biosynthetic Regulome
por: Mülleder, Michael, et al.
Publicado: (2016)

Single-cell regulome data analysis by SCRAT
por: Ji, Zhicheng, et al.
Publicado: (2017)

Towards the complete proteinaceous regulome of Acinetobacter baumannii
por: Casella, Leila G, et al.
Publicado: (2017)

The tRNA regulome in neurodevelopmental and neuropsychiatric disease
por: Blaze, Jennifer, et al.
Publicado: (2022)

Microarray Analysis of Bacterial Gene Expression: Towards the Regulome
por: Kendall, Sharon L., et al.
Publicado: (2002)

σ(54)-dependent regulome in Desulfovibrio vulgaris Hildenborough
por: Kazakov, Alexey E., et al.
Publicado: (2015)

Annotation of functional variation in personal genomes using RegulomeDB
por: Boyle, Alan P., et al.
Publicado: (2012)

The Effect of Belantamab Mafodotin on Primary Myeloma–Stroma Co-Cultures: Asymmetrical Mitochondrial Transfer between Myeloma Cells and Autologous Bone Marrow Stromal Cells
por: Matula, Zsolt, et al.
Publicado: (2023)

Emerging combination therapies for the management of multiple myeloma: the role of elotuzumab
por: Chen, Wei-Chih, et al.
Publicado: (2017)

Modeling the Pseudomonas Sulfur Regulome by Quantifying the Storage and Communication of Information
por: Larsen, Peter E., et al.
Publicado: (2018)

Tick Importin-α Is Implicated in the Interactome and Regulome of the Cofactor Subolesin
por: Artigas-Jerónimo, Sara, et al.
Publicado: (2021)

Regulome-based characterization of drug activity across the human diseasome
por: Iwata, Michio, et al.
Publicado: (2022)

Inferring and perturbing cell fate regulomes in human brain organoids
por: Fleck, Jonas Simon, et al.
Publicado: (2022)

The predicted RNA-binding protein regulome of axonal mRNAs
por: Luisier, Raphaëlle, et al.
Publicado: (2023)

Evolutionary Dynamics of Tumor-Stroma Interactions in Multiple Myeloma
por: Sartakhti, Javad Salimi, et al.
Publicado: (2016)

The pathogenetic influence of smoking on SARS-CoV-2 infection: Integrative transcriptome and regulomics analysis of lung epithelial cells
por: Ali Hossain, Md., et al.
Publicado: (2023)

Interdisciplinary Inquiry via PanelGPT: Application to Explore Chatbot Application in Sports Rehabilitation
por: McBee, Joseph C., et al.
Publicado: (2023)

An approach for determining and measuring network hierarchy applied to comparing the phosphorylome and the regulome
por: Cheng, Chao, et al.
Publicado: (2015)

ChIP-Hub provides an integrative platform for exploring plant regulome
por: Fu, Liang-Yu, et al.
Publicado: (2022)

Resistance of bone marrow stroma to genotoxic preconditioning is determined by p53
por: Fedtsova, Natalia, et al.
Publicado: (2021)

Rare disruptive variants in the DISC1 Interactome and Regulome: association with cognitive ability and schizophrenia
por: Teng, S, et al.
Publicado: (2018)

Investigation of Gene Expressions of Myeloma Cells in the Bone Marrow of Multiple Myeloma Patients by Transcriptome Analysis
por: Sarıman, Melda, et al.
Publicado: (2019)

Selective inhibition of matrix metalloproteinase-2 in the multiple myeloma-bone microenvironment
por: Shay, Gemma, et al.
Publicado: (2017)

Prenatal Cadmium Exposure Alters Proliferation in Mouse CD4(+) T Cells via LncRNA Snhg7
por: McCall, Jamie L., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_drn35p0nn4u4d631dls15hnrmg