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Quantitative Analysis of Plasma Cell-Free DNA and Its DNA Integrity and Hypomethylation Status as Biomarkers for Tumor Burden and Disease Progression in Patients with Metastatic Neuroendocrine Neoplasias

SIMPLE SUMMARY: Neuroendocrine neoplasias (NEN) are a heterogeneous group of frequent slow-progressing malignant tumors for which a reliable marker for tumor relapse and progression is still lacking. Previously, circulating cell-free DNA and its global methylation status and fragmentation rate have...

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Detalles Bibliográficos
Autores principales: Mettler, Esther, Fottner, Christian, Bakhshandeh, Neda, Trenkler, Anja, Kuchen, Robert, Weber, Matthias M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870292/
https://www.ncbi.nlm.nih.gov/pubmed/35205773
http://dx.doi.org/10.3390/cancers14041025