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Quantitative Analysis of Plasma Cell-Free DNA and Its DNA Integrity and Hypomethylation Status as Biomarkers for Tumor Burden and Disease Progression in Patients with Metastatic Neuroendocrine Neoplasias

SIMPLE SUMMARY: Neuroendocrine neoplasias (NEN) are a heterogeneous group of frequent slow-progressing malignant tumors for which a reliable marker for tumor relapse and progression is still lacking. Previously, circulating cell-free DNA and its global methylation status and fragmentation rate have...

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Detalles Bibliográficos
Autores principales:	Mettler, Esther, Fottner, Christian, Bakhshandeh, Neda, Trenkler, Anja, Kuchen, Robert, Weber, Matthias M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870292/ https://www.ncbi.nlm.nih.gov/pubmed/35205773 http://dx.doi.org/10.3390/cancers14041025

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