HPRT1 Promotes Chemoresistance in Oral Squamous Cell Carcinoma via Activating MMP1/PI3K/Akt Signaling Pathway

SIMPLE SUMMARY: Hypoxanthine phosphoribosyl transferase 1 (HPRT1) is traditionally believed to be a housekeeping gene, however, we found that highly expressed HPRT1 was associated with a poor prognosis and could promote resistance to cisplatin (CDDP) in OSCC cells in both in vitro and in vivo. Hence...

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Detalles Bibliográficos
Autores principales: Wu, Tong, Jiao, Zan, Li, Yixuan, Su, Xuan, Yao, Fan, Peng, Jin, Chen, Weichao, Yang, Ankui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870334/
https://www.ncbi.nlm.nih.gov/pubmed/35205603
http://dx.doi.org/10.3390/cancers14040855

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870334/
https://www.ncbi.nlm.nih.gov/pubmed/35205603
http://dx.doi.org/10.3390/cancers14040855

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