Toward More Comprehensive Homologous Recombination Deficiency Assays in Ovarian Cancer Part 2: Medical Perspectives

SIMPLE SUMMARY: High-grade serous ovarian cancer (HGSOC—the most frequent and aggressive form of ovarian cancer) represents an important challenge for clinicians. Half of HGSOC cases exhibit homologous recombination deficiency (HRD), mainly through alterations in BRCA1 and BRCA2. This leads to sensi...

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Detalles Bibliográficos
Autores principales: Quesada, Stanislas, Fabbro, Michel, Solassol, Jérôme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870335/
https://www.ncbi.nlm.nih.gov/pubmed/35205846
http://dx.doi.org/10.3390/cancers14041098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870335/
https://www.ncbi.nlm.nih.gov/pubmed/35205846
http://dx.doi.org/10.3390/cancers14041098

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