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Everything Comes with a Price: The Toxicity Profile of DNA-Damage Response Targeting Agents
SIMPLE SUMMARY: DNA damage induces genome instability, which may elicit cancer development. Defects in the DNA repair machinery further enhance cancer predisposition, but can also be exploited as a therapeutic target. Indeed, targeted agents against specific components of DNA repair, such as PARP in...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870347/ https://www.ncbi.nlm.nih.gov/pubmed/35205700 http://dx.doi.org/10.3390/cancers14040953 |