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Re-Discovery of Pyrimidine Salvage as Target in Cancer Therapy
Nucleotides are synthesized through two distinct pathways: de novo synthesis and nucleoside salvage. Whereas the de novo pathway synthesizes nucleotides from amino acids and glucose, the salvage pathway recovers nucleosides or bases formed during DNA or RNA degradation. In contrast to high prolifera...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870348/ https://www.ncbi.nlm.nih.gov/pubmed/35203388 http://dx.doi.org/10.3390/cells11040739 |