Urokinase Receptor uPAR Downregulation in Neuroblastoma Leads to Dormancy, Chemoresistance and Metastasis

SIMPLE SUMMARY: uPAR is a membrane receptor that contributes to extracellular matrix remodeling and controls cellular adhesion, proliferation, survival, and migration. We demonstrate that the initially high uPAR expression predicts poor survival in neuroblastoma. However, relapsed neuroblastomas hav...

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Detalles Bibliográficos
Autores principales: Shmakova, Anna A., Klimovich, Polina S., Rysenkova, Karina D., Popov, Vladimir S., Gorbunova, Anna S., Karpukhina, Anna A., Karagyaur, Maxim N., Rubina, Kseniya A., Tkachuk, Vsevolod A., Semina, Ekaterina V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870350/
https://www.ncbi.nlm.nih.gov/pubmed/35205745
http://dx.doi.org/10.3390/cancers14040994

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870350/
https://www.ncbi.nlm.nih.gov/pubmed/35205745
http://dx.doi.org/10.3390/cancers14040994

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