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Novel Insights on the Use of L-Asparaginase as an Efficient and Safe Anti-Cancer Therapy

SIMPLE SUMMARY: L-asparaginase (L-ASNase) therapy is key for achieving the very high cure rate of pediatric acute lymphoblastic leukemia (ALL), yet its use is mostly confined to this indication. One main reason preventing the expansion of today’s FDA-approved L-ASNases to solid cancers is their high...

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Detalles Bibliográficos
Autores principales: Van Trimpont, Maaike, Peeters, Evelien, De Visser, Yanti, Schalk, Amanda M., Mondelaers, Veerle, De Moerloose, Barbara, Lavie, Arnon, Lammens, Tim, Goossens, Steven, Van Vlierberghe, Pieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870365/
https://www.ncbi.nlm.nih.gov/pubmed/35205650
http://dx.doi.org/10.3390/cancers14040902