Patient-Derived Ovarian Cancer Spheroids Rely on PI3K-AKT Signaling Addiction for Cancer Stemness and Chemoresistance

SIMPLE SUMMARY: Epithelial ovarian cancer (EOC) is the most fatal gynecological cancer with poor survival rates and high mortality. EOC patients respond to standard platinum-based chemotherapy in the beginning, but relapse often due to chemoresistance. Ovarian cancer cells disseminate from the ovari...

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Detalles Bibliográficos
Autores principales: Parashar, Deepak, Geethadevi, Anjali, Mittal, Sonam, McAlarnen, Lindsey A., George, Jasmine, Kadamberi, Ishaque P., Gupta, Prachi, Uyar, Denise S., Hopp, Elizabeth E., Drendel, Holli, Bishop, Erin A., Bradley, William H., Bone, Kathleen M., Rader, Janet S., Pradeep, Sunila, Chaluvally-Raghavan, Pradeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870411/
https://www.ncbi.nlm.nih.gov/pubmed/35205706
http://dx.doi.org/10.3390/cancers14040958

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870411/
https://www.ncbi.nlm.nih.gov/pubmed/35205706
http://dx.doi.org/10.3390/cancers14040958

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