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Identification of Tissue-Specific Gene Clusters Induced by DNA Demethylation in Lung Adenocarcinoma: More Than Germline Genes

SIMPLE SUMMARY: Loss of DNA methylation is often observed in human tumors, but how this epigenetic alteration impacts the transcriptome of cancer cells remains largely undefined. So far, DNA hypomethylation in tumors has been associated with aberrant activation of a germline-specific gene expression...

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Detalles Bibliográficos
Autores principales: Diacofotaki, Anna, Loriot, Axelle, De Smet, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870412/
https://www.ncbi.nlm.nih.gov/pubmed/35205751
http://dx.doi.org/10.3390/cancers14041007