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Altered Phenotype and Enhanced Antibody-Producing Ability of Peripheral B Cells in Mice with Cd19-Driven Cre Expression

Given the importance of B lymphocytes in inflammation and immune defense against pathogens, mice transgenic for Cre under the control of Cd19 promoter (Cd19(Cre/+) mice) have been widely used to specifically investigate the role of loxP-flanked genes in B cell development/function. However, impacts...

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Detalles Bibliográficos
Autores principales: Zhao, Ying, Zhao, Sai, Qin, Xiao-Yuan, He, Ting-Ting, Hu, Miao-Miao, Gong, Zheng, Wang, Hong-Min, Gong, Fang-Yuan, Gao, Xiao-Ming, Wang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870415/
https://www.ncbi.nlm.nih.gov/pubmed/35203346
http://dx.doi.org/10.3390/cells11040700