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Activation of ABCC Genes by Cisplatin Depends on the CoREST Occurrence at Their Promoters in A549 and MDA-MB-231 Cell Lines

SIMPLE SUMMARY: Cisplatin resistance is a common issue that affects patients with a variety of cancers who are treated with this drug. In this research, we present a novel epigenetic mechanism that controls the expression of ABC-family transporters, which are involved in multidrug resistance. We rep...

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Detalles Bibliográficos
Autores principales: Sobczak, Maciej, Strachowska, Magdalena, Gronkowska, Karolina, Robaszkiewicz, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870433/
https://www.ncbi.nlm.nih.gov/pubmed/35205642
http://dx.doi.org/10.3390/cancers14040894