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Evolutionary information helps understand distinctive features of the angiotensin II receptors AT1 and AT2 in amniota

In vertebrates, the octopeptide angiotensin II (AngII) is an important in vivo regulator of the cardiovascular system. It acts mainly through two G protein-coupled receptors, AT1 and AT2. To better understand distinctive features of these receptors, we carried out a phylogenetic analysis that reveal...

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Detalles Bibliográficos
Autores principales: Ben Boubaker, Rym, Tiss, Asma, Henrion, Daniel, Guissouma, Hajer, Chabbert, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870451/
https://www.ncbi.nlm.nih.gov/pubmed/35202400
http://dx.doi.org/10.1371/journal.pcbi.1009732