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Dual Targeting of PI3K and HDAC by CUDC-907 Inhibits Pediatric Neuroblastoma Growth

SIMPLE SUMMARY: High-risk neuroblastoma (NB) is an aggressive cancer of very young children and accounts for almost 15% of all pediatric cancer deaths. Current therapies include high-dose chemotherapy and radiation, which have long-term toxic side effects. Despite these intensive therapies, the over...

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Detalles Bibliográficos
Autores principales: Chilamakuri, Rameswari, Agarwal, Saurabh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870466/
https://www.ncbi.nlm.nih.gov/pubmed/35205815
http://dx.doi.org/10.3390/cancers14041067