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Genetic dissection of novel myopathy models reveals a role of CapZα and Leiomodin 3 during myofibril elongation

Myofibrils within skeletal muscle are composed of sarcomeres that generate force by contraction when their myosin-rich thick filaments slide past actin-based thin filaments. Although mutations in components of the sarcomere are a major cause of human disease, the highly complex process of sarcomere...

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Detalles Bibliográficos
Autores principales: Berger, Joachim, Berger, Silke, Mok, Yu Shan G., Li, Mei, Tarakci, Hakan, Currie, Peter D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870547/
https://www.ncbi.nlm.nih.gov/pubmed/35148320
http://dx.doi.org/10.1371/journal.pgen.1010066