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Genetic dissection of novel myopathy models reveals a role of CapZα and Leiomodin 3 during myofibril elongation
Myofibrils within skeletal muscle are composed of sarcomeres that generate force by contraction when their myosin-rich thick filaments slide past actin-based thin filaments. Although mutations in components of the sarcomere are a major cause of human disease, the highly complex process of sarcomere...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870547/ https://www.ncbi.nlm.nih.gov/pubmed/35148320 http://dx.doi.org/10.1371/journal.pgen.1010066 |