Cargando…
Genetic dissection of novel myopathy models reveals a role of CapZα and Leiomodin 3 during myofibril elongation
Myofibrils within skeletal muscle are composed of sarcomeres that generate force by contraction when their myosin-rich thick filaments slide past actin-based thin filaments. Although mutations in components of the sarcomere are a major cause of human disease, the highly complex process of sarcomere...
Autores principales: | Berger, Joachim, Berger, Silke, Mok, Yu Shan G., Li, Mei, Tarakci, Hakan, Currie, Peter D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870547/ https://www.ncbi.nlm.nih.gov/pubmed/35148320 http://dx.doi.org/10.1371/journal.pgen.1010066 |
Ejemplares similares
-
Identification and characterization of an actin-binding site of CapZ
Publicado: (1992) -
CapZ-lipid membrane interactions: a computer analysis
por: Smith, James, et al.
Publicado: (2006) -
Inhibition of CapZ during myofibrillogenesis alters assembly of actin filaments
Publicado: (1995) -
CapZ integrates several signaling pathways in response to mechanical stiffness
por: Solís, Christopher, et al.
Publicado: (2019) -
Direct observation of actin filament severing by gelsolin and binding by gCap39 and CapZ
por: Bearer, EL
Publicado: (1991)