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Identification of potential functional variants and genes at 18q21.1 associated with the carcinogenesis of colorectal cancer
Genome-wide association studies (GWAS) have identified more than 160 susceptibility loci for colorectal cancer (CRC). The effects of these variants, particularly their mechanisms, however, remain unclear. In this study, a comprehensive functional annotation of CRC-related GWAS signals was firstly co...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870576/ https://www.ncbi.nlm.nih.gov/pubmed/35108261 http://dx.doi.org/10.1371/journal.pgen.1010050 |