Characterisation of the spectrum and genetic dependence of collateral mutations induced by translesion DNA synthesis

Translesion DNA synthesis (TLS) is a fundamental damage bypass pathway that utilises specialised polymerases with relaxed template specificity to achieve replication through damaged DNA. Misinsertions by low fidelity TLS polymerases may introduce additional mutations on undamaged DNA near the origin...

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Detalles Bibliográficos
Autores principales: Póti, Ádám, Szikriszt, Bernadett, Gervai, Judit Zsuzsanna, Chen, Dan, Szüts, Dávid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870599/
https://www.ncbi.nlm.nih.gov/pubmed/35130276
http://dx.doi.org/10.1371/journal.pgen.1010051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870599/
https://www.ncbi.nlm.nih.gov/pubmed/35130276
http://dx.doi.org/10.1371/journal.pgen.1010051

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