Epigenetic Dysregulation of the Homeobox A5 (HOXA5) Gene Associates with Subcutaneous Adipocyte Hypertrophy in Human Obesity

Along with insulin resistance and increased risk of type 2 diabetes (T2D), lean first-degree relatives of T2D subjects (FDR) feature impaired adipogenesis in subcutaneous adipose tissue (SAT) and subcutaneous adipocyte hypertrophy well before diabetes onset. The molecular mechanisms linking these ev...

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Detalles Bibliográficos
Autores principales: Parrillo, Luca, Spinelli, Rosa, Costanzo, Mattia, Florese, Pasqualina, Cabaro, Serena, Desiderio, Antonella, Prevenzano, Immacolata, Raciti, Gregory Alexander, Smith, Ulf, Miele, Claudia, Formisano, Pietro, Napoli, Raffaele, Beguinot, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870634/
https://www.ncbi.nlm.nih.gov/pubmed/35203377
http://dx.doi.org/10.3390/cells11040728

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870634/
https://www.ncbi.nlm.nih.gov/pubmed/35203377
http://dx.doi.org/10.3390/cells11040728

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