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Treatment of Experimental Autoimmune Encephalomyelitis with an Inhibitor of Phosphodiesterase-8 (PDE8)

After decades of development, inhibitors targeting cyclic nucleotide phosphodiesterases (PDEs) expressed in leukocytes have entered clinical practice for the treatment of inflammatory disorders, with three PDE4 inhibitors being in clinical use as therapeutics for psoriasis, psoriatic arthritis, chro...

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Detalles Bibliográficos
Autores principales: Basole, Chaitali P., Nguyen, Rebecca K., Lamothe, Katie, Billis, Puja, Fujiwara, Mai, Vang, Amanda G., Clark, Robert B., Epstein, Paul M., Brocke, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870644/
https://www.ncbi.nlm.nih.gov/pubmed/35203312
http://dx.doi.org/10.3390/cells11040660