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Hyperactivation of MAPK Induces Tamoxifen Resistance in SPRED2-Deficient ERα-Positive Breast Cancer

SIMPLE SUMMARY: Tamoxifen has been used for more than 40 years to treat breast tumors that are dependent on the hormone estrogen for their growth. However, resistance and recurrence of the tumors during the course of the treatment are common. Understanding the mechanisms that drive tamoxifen resista...

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Detalles Bibliográficos
Autores principales: Vafeiadou, Vasiliki, Hany, Dina, Picard, Didier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870665/
https://www.ncbi.nlm.nih.gov/pubmed/35205702
http://dx.doi.org/10.3390/cancers14040954