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Fast and Accurate Surrogate Virus Neutralization Test Based on Antibody-Mediated Blocking of the Interaction of ACE2 and SARS-CoV-2 Spike Protein RBD

The humoral response to the SARS-CoV-2 S protein determines the development of protective immunity against this infection. The standard neutralizing antibodies detection method is a live virus neutralization test. It can be replaced with an ELISA-based surrogate virus neutralization test (sVNT), mea...

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Detalles Bibliográficos
Autores principales: Kolesov, Denis E., Sinegubova, Maria V., Dayanova, Lutsia K., Dolzhikova, Inna V., Vorobiev, Ivan I., Orlova, Nadezhda A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870830/
https://www.ncbi.nlm.nih.gov/pubmed/35204485
http://dx.doi.org/10.3390/diagnostics12020393