Identification of microRNAs Implicated in Modulating Senecionine-Induced Liver Toxicity in HepaRG Cells

1,2-unsaturated Pyrrolizidine Alkaloids (PAs) are secondary plant metabolites that occur as food contaminants. Upon consumption, they can cause severe liver damage. PAs have been shown to induce apoptosis, to have cytotoxic and genotoxic effects, and to impair bile acid homeostasis in the human hepa...

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Detalles Bibliográficos
Autores principales: Enge, Anne-Margarethe, Sprenger, Heike, Braeuning, Albert, Hessel-Pras, Stefanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8871147/
https://www.ncbi.nlm.nih.gov/pubmed/35206009
http://dx.doi.org/10.3390/foods11040532

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8871147/
https://www.ncbi.nlm.nih.gov/pubmed/35206009
http://dx.doi.org/10.3390/foods11040532

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