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Evaluation of MMR Status and PD-L1 Expression Using Specimens Obtained by EUS-FNB in Patients with Pancreatic Ductal Adenocarcinoma (PDAC)

Deficient DNA mismatch repair status (dMMR)/high microsatellite instability have been shown to be predictive biomarkers for immune checkpoint inhibitor drugs which block the programmed death protein-1/programmed death ligand-1 (PD-1/PD-L1) interaction between tumor cells and activated T cells. The a...

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Detalles Bibliográficos
Autores principales: Constantin, Alina, Iovănescu, Vlad, Cazacu, Irina Mihaela, Ungureanu, Bogdan Silviu, Copăescu, Cătălin, Stroescu, Cezar, Bejinariu, Nona, Săftoiu, Adrian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8871161/
https://www.ncbi.nlm.nih.gov/pubmed/35204385
http://dx.doi.org/10.3390/diagnostics12020294