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Evaluation of MMR Status and PD-L1 Expression Using Specimens Obtained by EUS-FNB in Patients with Pancreatic Ductal Adenocarcinoma (PDAC)
Deficient DNA mismatch repair status (dMMR)/high microsatellite instability have been shown to be predictive biomarkers for immune checkpoint inhibitor drugs which block the programmed death protein-1/programmed death ligand-1 (PD-1/PD-L1) interaction between tumor cells and activated T cells. The a...
Autores principales: | Constantin, Alina, Iovănescu, Vlad, Cazacu, Irina Mihaela, Ungureanu, Bogdan Silviu, Copăescu, Cătălin, Stroescu, Cezar, Bejinariu, Nona, Săftoiu, Adrian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8871161/ https://www.ncbi.nlm.nih.gov/pubmed/35204385 http://dx.doi.org/10.3390/diagnostics12020294 |
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