The Cl(-)-channel TMEM16A is involved in the generation of cochlear Ca(2+) waves and promotes the refinement of auditory brainstem networks in mice

Before hearing onset (postnatal day 12 in mice), inner hair cells (IHCs) spontaneously fire action potentials, thereby driving pre-sensory activity in the ascending auditory pathway. The rate of IHC action potential bursts is modulated by inner supporting cells (ISCs) of Kölliker’s organ through the...

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Detalles Bibliográficos
Autores principales: Maul, Alena, Huebner, Antje Kathrin, Strenzke, Nicola, Moser, Tobias, Rübsamen, Rudolf, Jovanovic, Saša, Hübner, Christian A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8871368/
https://www.ncbi.nlm.nih.gov/pubmed/35129434
http://dx.doi.org/10.7554/eLife.72251

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8871368/
https://www.ncbi.nlm.nih.gov/pubmed/35129434
http://dx.doi.org/10.7554/eLife.72251

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