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Complex effects of kinase localization revealed by compartment-specific regulation of protein kinase A activity

Kinase activity in signaling networks frequently depends on regulatory subunits that can both inhibit activity by interacting with the catalytic subunits and target the kinase to distinct molecular partners and subcellular compartments. Here, using a new synthetic molecular interaction system, we sh...

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Detalles Bibliográficos
Autores principales: LaCroix, Rebecca, Lin, Benjamin, Kang, Tae-Yun, Levchenko, Andre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8871369/
https://www.ncbi.nlm.nih.gov/pubmed/35199643
http://dx.doi.org/10.7554/eLife.66869