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Complex effects of kinase localization revealed by compartment-specific regulation of protein kinase A activity
Kinase activity in signaling networks frequently depends on regulatory subunits that can both inhibit activity by interacting with the catalytic subunits and target the kinase to distinct molecular partners and subcellular compartments. Here, using a new synthetic molecular interaction system, we sh...
Autores principales: | LaCroix, Rebecca, Lin, Benjamin, Kang, Tae-Yun, Levchenko, Andre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8871369/ https://www.ncbi.nlm.nih.gov/pubmed/35199643 http://dx.doi.org/10.7554/eLife.66869 |
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