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Zinc finger protein Zfp335 controls early T-cell development and survival through β-selection-dependent and -independent mechanisms

T-cell development in the thymus undergoes the process of differentiation, selective proliferation, and survival from CD4(−)CD8(−) double negative (DN) stage to CD4(+)CD8(+) double positive (DP) stage prior to the formation of CD4(+) helper and CD8(+) cytolytic T cells ready for circulation. Each de...

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Detalles Bibliográficos
Autores principales: Wang, Xin, Jiao, Anjun, Sun, Lina, Li, Wenhua, Yang, Biao, Su, Yanhong, Ding, Renyi, Zhang, Cangang, Liu, Haiyan, Yang, Xiaofeng, Sun, Chenming, Zhang, Baojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8871394/
https://www.ncbi.nlm.nih.gov/pubmed/35113015
http://dx.doi.org/10.7554/eLife.75508