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Tacrolimus-Loaded Solid Lipid Nanoparticle Gel: Formulation Development and In Vitro Assessment for Topical Applications

The currently available topical formulations of tacrolimus have minimal and variable absorption, elevated mean disposition half-life, and skin irritation effects resulting in patient noncompliance. In our study, we fabricated tacrolimus-loaded solid lipid nanoparticles (SLNs) that were converted int...

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Detalles Bibliográficos
Autores principales: Khan, Abdul Shakur, Shah, Kifayat Ullah, Mohaini, Mohammed Al, Alsalman, Abdulkhaliq J., Hawaj, Maitham A. Al, Alhashem, Yousef N., Ghazanfar, Shakira, Khan, Kamran Ahmad, Niazi, Zahid Rasul, Farid, Arshad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8871527/
https://www.ncbi.nlm.nih.gov/pubmed/35200510
http://dx.doi.org/10.3390/gels8020129