Cargando…

Tacrolimus-Loaded Solid Lipid Nanoparticle Gel: Formulation Development and In Vitro Assessment for Topical Applications

The currently available topical formulations of tacrolimus have minimal and variable absorption, elevated mean disposition half-life, and skin irritation effects resulting in patient noncompliance. In our study, we fabricated tacrolimus-loaded solid lipid nanoparticles (SLNs) that were converted int...

Descripción completa

Detalles Bibliográficos
Autores principales:	Khan, Abdul Shakur, Shah, Kifayat Ullah, Mohaini, Mohammed Al, Alsalman, Abdulkhaliq J., Hawaj, Maitham A. Al, Alhashem, Yousef N., Ghazanfar, Shakira, Khan, Kamran Ahmad, Niazi, Zahid Rasul, Farid, Arshad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8871527/ https://www.ncbi.nlm.nih.gov/pubmed/35200510 http://dx.doi.org/10.3390/gels8020129

Ejemplares similares

Preparation of Losartan Potassium Controlled Release Matrices and In-Vitro Investigation Using Rate Controlling Agents
por: Khan, Kamran Ahmad, et al.
Publicado: (2022)

In Silico Analysis of the L-2-Hydroxyglutarate Dehydrogenase Gene Mutations and Their Biological Impact on Disease Etiology
por: Muzammal, Muhammad, et al.
Publicado: (2022)

Formulation and Characterization of Chitosan-Decorated Multiple Nanoemulsion for Topical Delivery In Vitro and Ex Vivo
por: Malik, Muhammad Rehan, et al.
Publicado: (2022)

Formulation and Evaluation of Hydrophilic Polymer Based Methotrexate Patches: In Vitro and In Vivo Characterization
por: Latif, Muhammad Shahid, et al.
Publicado: (2022)

In Vitro and Ex Vivo Evaluation of Fluocinolone Acetonide–Acitretin-Coloaded Nanostructured Lipid Carriers for Topical Treatment of Psoriasis
por: Raza, Hassan, et al.
Publicado: (2022)

In Silico Analysis Identified Putative Pathogenic Missense nsSNPs in Human SLITRK1 Gene
por: Ali, Muhammad Zeeshan, et al.
Publicado: (2022)

Obviation of dyslipidemia by garlic oil and its organosulfur compound, diallyl disulphide, in experimental animals
por: Mohammed Basheeruddin Asdaq, Syed, et al.
Publicado: (2022)

Insights into the Protective Effects of Thymoquinone against Toxicities Induced by Chemotherapeutic Agents
por: Farooq, Juveriya, et al.
Publicado: (2021)

The role of serotonergic and catecholaminergic systems for possible antidepressant activity of apigenin
por: Al-Yamani, Mohammad J., et al.
Publicado: (2022)

Preparation and In Vitro Evaluation of Controlled-Release Matrices of Losartan Potassium Using Ethocel Grade 10 and Carbopol 934P NF as Rate-Controlling Polymers
por: Khan, Kamran Ahmad, et al.
Publicado: (2022)

Wireless Networking-Driven Healthcare Approaches in Combating COVID-19
por: BasheeruddinAsdaq, Syed Mohammed, et al.
Publicado: (2021)

Elevated Vulnerability of Chronic Leukemia Patients to COVID-19 Infection: A Systems Biology Approach
por: Alsalman, Abdulkhaliq J., et al.
Publicado: (2022)

Formulation Development and Ex-Vivo Permeability of Curcumin Hydrogels under the Influence of Natural Chemical Enhancers
por: Nawaz, Asif, et al.
Publicado: (2022)

Physicochemical Characterization of Chitosan-Decorated Finasteride Solid Lipid Nanoparticles for Skin Drug Delivery
por: Sohaib, Muhammad, et al.
Publicado: (2022)

Polymeric Microparticles: Synthesis, Characterization and In Vitro Evaluation for Pulmonary Delivery of Rifampicin
por: Naz, Faiqa Falak, et al.
Publicado: (2022)

Nanocrytals-Mediated Oral Drug Delivery: Enhanced Bioavailability of Amiodarone
por: Awan, Anum Munir, et al.
Publicado: (2022)

Preparation and Characterization of Controlled-Release Floating Bilayer Tablets of Esomeprazole and Clarithromycin
por: Israr, Muhammad, et al.
Publicado: (2022)

Three-Dimensional Structure Characterization and Inhibition Study of Exfoliative Toxin D From Staphylococcus aureus
por: Ullah, Anwar, et al.
Publicado: (2022)

On different results for new three step iteration process in Banach spaces
por: Ullah, Kifayat, et al.
Publicado: (2016)

Formulation and Evaluation of Transdermal Gel Containing Tacrolimus-Loaded Spanlastics: In Vitro, Ex Vivo and In Vivo Studies
por: Zaki, Randa Mohammed, et al.
Publicado: (2022)

Regulating Drug Release Behavior and Kinetics from Matrix Tablets Based on Fine Particle-Sized Ethyl Cellulose Ether Derivatives: An In Vitro and In Vivo Evaluation
por: Shah, Kifayat Ullah, et al.
Publicado: (2012)

Folate-Modified Chitosan 5-Flourouraci Nanoparticles-Embedded Calcium Alginate Beads for Colon Targeted Delivery
por: Ullah, Shafi, et al.
Publicado: (2022)

Synthesis and Characterization of Carboxymethyl Chitosan Nanosponges with Cyclodextrin Blends for Drug Solubility Improvement
por: Rizvi, Syeda Sadia Batool, et al.
Publicado: (2022)

Highly Responsive Chitosan-Co-Poly (MAA) Nanomatrices through Cross-Linking Polymerization for Solubility Improvement
por: Saleem, Anam, et al.
Publicado: (2022)

In-Silico Characterization of Estrogen Reactivating β-Glucuronidase Enzyme in GIT Associated Microbiota of Normal Human and Breast Cancer Patients
por: Muccee, Fatima, et al.
Publicado: (2022)

EHHR: an efficient evolutionary hyper-heuristic based recommender framework for short-text classifier selection
por: Almas, Bushra, et al.
Publicado: (2022)

Lornoxicam-Loaded Chitosan-Decorated Nanoemulsion: Preparation and In Vitro Evaluation for Enhanced Transdermal Delivery
por: Khan, Rahman Ullah, et al.
Publicado: (2022)

Development and Evaluation of Essential Oil-Based Nanoemulgel Formulation for the Treatment of Oral Bacterial Infections
por: Ullah, Niamat, et al.
Publicado: (2023)

Probiotics (Bacillus clausii and Lactobacillus fermentum NMCC-14) Ameliorate Stress Behavior in Mice by Increasing Monoamine Levels and mRNA Expression of Dopamine Receptors (D(1) and D(2)) and Synaptophysin
por: Rehman, Mujeeb Ur, et al.
Publicado: (2022)

Immune Persistence After Infant Hepatitis-B Vaccination: A Systematic Review and Meta-Analysis
por: Mahmood, Sajid, et al.
Publicado: (2018)

Formulation and characterization of lornoxicam-loaded cellulosic-microsponge gel for possible applications in arthritis
por: He, Yeteng, et al.
Publicado: (2020)

Formulation and Evaluation of Diclofenac Potassium Gel in Sports Injuries with and without Phonophoresis
por: Bukhari, Komal Ammar, et al.
Publicado: (2022)

The Intercalation of CORM-2 with Pharmaceutical Clay Montmorillonite (MMT) Aids for Therapeutic Carbon Monoxide Release
por: Faizan, Muhammad, et al.
Publicado: (2019)

Synthesis, structural characterization and catalytic application of citrate-stabilized monometallic and bimetallic palladium@copper nanoparticles in microbial anti-activities
por: Ullah, Inayat, et al.
Publicado: (2017)

A Review on the Modification of Cellulose and Its Applications
por: Aziz, Tariq, et al.
Publicado: (2022)

The Effect of Intracellular Tacrolimus Exposure on Calcineurin Inhibition in Immediate- and Extended-Release Tacrolimus Formulations
por: Fontova, Pere, et al.
Publicado: (2023)

A randomized crossover study comparing different tacrolimus formulations to reduce intrapatient variability in tacrolimus exposure in kidney transplant recipients
por: Bunthof, Kim L. W., et al.
Publicado: (2021)

Employment of Alginate Floating In Situ Gel for Controlled Delivery of Celecoxib: Solubilization and Formulation Studies
por: Abdul Rasool, Bazigha K., et al.
Publicado: (2020)

Tacrolimus Ointment for Treatment of Vernal Keratoconjunctivitis
por: Al-Amri, Abdulrahman M., et al.
Publicado: (2016)

Application of Sucrose Acetate Isobutyrate in Development of Co-Amorphous Formulations of Tacrolimus for Bioavailability Enhancement
por: Mohamed, Eman M., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_hb3v9almporrmhh56m6574pttp