Induction of ROS and DNA damage-dependent senescence by icaritin contributes to its antitumor activity in hepatocellular carcinoma cells

Context: Icaritin (ICT), a prenylflavonoid derivative extracted from the Epimedium (Berberidaceae) genus, has been identified to exhibit antitumor effect in hepatocellular carcinoma (HCC) cells by inducing apoptosis. However, its effect on cellular senescence has not been elucidated. Objective: To i...

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Detalles Bibliográficos
Autores principales: Wang, Shikang, Wang, Qian, Wang, Huijun, Qin, Chengkun, Cui, Xianping, Li, Lei, Liu, Yongqing, Chang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8871611/
https://www.ncbi.nlm.nih.gov/pubmed/31407933
http://dx.doi.org/10.1080/13880209.2019.1628073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8871611/
https://www.ncbi.nlm.nih.gov/pubmed/31407933
http://dx.doi.org/10.1080/13880209.2019.1628073

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