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Pogostone inhibits the activity of CYP3A4, 2C9, and 2E1 in vitro

CONTEXT: Pogostone possesses various pharmacological activities, which makes it widely used in the clinic. Its effect on the activity of cytochrome P450 enzymes (CYP450s) could guide its clinical combination. OBJECTIVE: To investigate the effect of pogostone on the activity of human CYP450s. MATERIA...

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Detalles Bibliográficos
Autores principales: Zhang, Guiying, Zhang, Yanping, Ma, Xianjie, Yang, Xin, Cai, Yuyan, Yin, Wenli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8871619/
https://www.ncbi.nlm.nih.gov/pubmed/33915070
http://dx.doi.org/10.1080/13880209.2021.1917630