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A Porous Reservoir-Backed Boronate Gel Microneedle for Efficient Skin Penetration and Sustained Glucose-Responsive Insulin Delivery

Recently, phenylboronic acid (PBA) gel containing microneedle (MN) technology with acute and sustained glucose-sensitive functionality has attracted significant research attention. Herein, we report a polyvinyl alcohol(PVA)-coated MNs patch with an interconnected porous gel drug reservoir for enhanc...

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Detalles Bibliográficos
Autores principales: Chen, Siyuan, Miyazaki, Takuya, Itoh, Michiko, Matsumoto, Hiroko, Moro-oka, Yuki, Tanaka, Miyako, Miyahara, Yuji, Suganami, Takayoshi, Matsumoto, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8871697/
https://www.ncbi.nlm.nih.gov/pubmed/35200456
http://dx.doi.org/10.3390/gels8020074