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The Interactive Effect of Genetic and Epigenetic Variations in FKBP5 and ApoE Genes on Anxiety and Brain EEG Parameters

FKBP51 is a key stress-responsive regulator of the hypothalamic–pituitary–adrenal axis. To elucidate the contribution of rs1360780 FKBP5 C/T alleles to aging and longevity, we genotyped FKBP5 in a cohort of 800 non-demented and Alzheimer’s disease (AD) subjects of different age, taking into account...

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Detalles Bibliográficos
Autores principales: Kuznetsova, Irina L., Ponomareva, Natalya V., Alemastseva, Ekaterina A., Manakhov, Andrey D., Andreeva, Tatyana V., Gusev, Fedor E., Rogaev, Evgeny I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8872390/
https://www.ncbi.nlm.nih.gov/pubmed/35205209
http://dx.doi.org/10.3390/genes13020164