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Multi-Level Analysis and Identification of Tumor Mutational Burden Genes across Cancer Types

Tumor mutational burden (TMB) is considered a potential biomarker for predicting the response and effect of immune checkpoint inhibitors (ICIs). However, there are still inconsistent standards of gene panels using next-generation sequencing and poor correlation between the TMB genes, immune cell inf...

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Detalles Bibliográficos
Autores principales: Wang, Shuangkuai, Tong, Yuantao, Zong, Hui, Xu, Xuewen, Crabbe, M. James C., Wang, Ying, Zhang, Xiaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8872466/
https://www.ncbi.nlm.nih.gov/pubmed/35205408
http://dx.doi.org/10.3390/genes13020365