scInTime: A Computational Method Leveraging Single-Cell Trajectory and Gene Regulatory Networks to Identify Master Regulators of Cellular Differentiation

Trajectory inference (TI) or pseudotime analysis has dramatically extended the analytical framework of single-cell RNA-seq data, allowing regulatory genes contributing to cell differentiation and those involved in various dynamic cellular processes to be identified. However, most TI analysis procedu...

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Detalles Bibliográficos
Autores principales: Xu, Qian, Li, Guanxun, Osorio, Daniel, Zhong, Yan, Yang, Yongjian, Lin, Yu-Te, Zhang, Xiuren, Cai, James J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8872487/
https://www.ncbi.nlm.nih.gov/pubmed/35205415
http://dx.doi.org/10.3390/genes13020371

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8872487/
https://www.ncbi.nlm.nih.gov/pubmed/35205415
http://dx.doi.org/10.3390/genes13020371

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