Systematic modeling-driven experiments identify distinct molecular clockworks underlying hierarchically organized pacemaker neurons

In metazoan organisms, circadian (∼24 h) rhythms are regulated by pacemaker neurons organized in a master–slave hierarchy. Although it is widely accepted that master pacemakers and slave oscillators generate rhythms via an identical negative feedback loop of transcription factor CLOCK (CLK) and repr...

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Detalles Bibliográficos
Autores principales: Jeong, Eui Min, Kwon, Miri, Cho, Eunjoo, Lee, Sang Hyuk, Kim, Hyun, Kim, Eun Young, Kim, Jae Kyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8872709/
https://www.ncbi.nlm.nih.gov/pubmed/35193959
http://dx.doi.org/10.1073/pnas.2113403119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8872709/
https://www.ncbi.nlm.nih.gov/pubmed/35193959
http://dx.doi.org/10.1073/pnas.2113403119

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