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Role of internal loop dynamics in antibiotic permeability of outer membrane porins

Gram-negative bacteria pose a serious public health concern due to resistance to many antibiotics, caused by the low permeability of their outer membrane (OM). Effective antibiotics use porins in the OM to reach the interior of the cell; thus, understanding permeation properties of OM porins is inst...

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Detalles Bibliográficos
Autores principales: Vasan, Archit Kumar, Haloi, Nandan, Ulrich, Rebecca Joy, Metcalf, Mary Elizabeth, Wen, Po-Chao, Metcalf, William W., Hergenrother, Paul J., Shukla, Diwakar, Tajkhorshid, Emad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8872756/
https://www.ncbi.nlm.nih.gov/pubmed/35193963
http://dx.doi.org/10.1073/pnas.2117009119