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Definition of a mouse microglial subset that regulates neuronal development and proinflammatory responses in the brain

Expression of Itgax (encoding the CD11c surface protein) and Spp1 (encoding osteopontin; OPN) has been associated with activated microglia that can develop in healthy brains and some neuroinflammatory disorders. However, whether CD11c and OPN expression is a consequence of microglial activation or r...

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Detalles Bibliográficos
Autores principales: Shen, Xianli, Qiu, Yiguo, Wight, Andrew E., Kim, Hye-Jung, Cantor, Harvey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8872761/
https://www.ncbi.nlm.nih.gov/pubmed/35177477
http://dx.doi.org/10.1073/pnas.2116241119