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Superantigens promote Staphylococcus aureus bloodstream infection by eliciting pathogenic interferon-gamma production

Staphylococcus aureus is a foremost bacterial pathogen responsible for a vast array of human diseases. Staphylococcal superantigens (SAgs) constitute a family of exotoxins from S. aureus that bind directly to major histocompatibility complex (MHC) class II and T cell receptors to drive extensive T c...

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Detalles Bibliográficos
Autores principales: Tuffs, Stephen W., Goncheva, Mariya I., Xu, Stacey X., Craig, Heather C., Kasper, Katherine J., Choi, Joshua, Flannagan, Ronald S., Kerfoot, Steven M., Heinrichs, David E., McCormick, John K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8872782/
https://www.ncbi.nlm.nih.gov/pubmed/35165181
http://dx.doi.org/10.1073/pnas.2115987119